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CMG helicase disassembly is controlled by replication fork DNA, replisome  components and a ubiquitin threshold | eLife
CMG helicase disassembly is controlled by replication fork DNA, replisome components and a ubiquitin threshold | eLife

Replication Fork Activation Is Enabled by a Single-Stranded DNA Gate in CMG  Helicase - ScienceDirect
Replication Fork Activation Is Enabled by a Single-Stranded DNA Gate in CMG Helicase - ScienceDirect

Mcm10 regulates the assembly of the CMG complex and DNA origin melting....  | Download Scientific Diagram
Mcm10 regulates the assembly of the CMG complex and DNA origin melting.... | Download Scientific Diagram

Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a  Replication Fork - ScienceDirect
Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork - ScienceDirect

DNA densities and interactions with CMG in the CMG-ssDNA structure. CMG...  | Download Scientific Diagram
DNA densities and interactions with CMG in the CMG-ssDNA structure. CMG... | Download Scientific Diagram

CryoEM structures of human CMG - ATPγS - DNA and CMG - AND-1 complexes |  bioRxiv
CryoEM structures of human CMG - ATPγS - DNA and CMG - AND-1 complexes | bioRxiv

Purification of the CMG complex. (A) Purification schematic. See the... |  Download Scientific Diagram
Purification of the CMG complex. (A) Purification schematic. See the... | Download Scientific Diagram

DNA binding polarity, dimerization, and ATPase ring remodeling in the CMG  helicase of the eukaryotic replisome | eLife
DNA binding polarity, dimerization, and ATPase ring remodeling in the CMG helicase of the eukaryotic replisome | eLife

CMG helicase disassembly is controlled by replication fork DNA, replisome  components and a ubiquitin threshold | eLife
CMG helicase disassembly is controlled by replication fork DNA, replisome components and a ubiquitin threshold | eLife

DNA binding polarity, dimerization, and ATPase ring remodeling in the CMG  helicase of the eukaryotic replisome | eLife
DNA binding polarity, dimerization, and ATPase ring remodeling in the CMG helicase of the eukaryotic replisome | eLife

Structure of eukaryotic CMG helicase at a replication fork and implications  to replisome architecture and origin initiation | PNAS
Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation | PNAS

Mechanisms in helicase activation and analysis of the replication fork  activity and architecture – Speck Lab / DNA Replication Group – Christian  Speck
Mechanisms in helicase activation and analysis of the replication fork activity and architecture – Speck Lab / DNA Replication Group – Christian Speck

Characterization of the dimeric CMG/pre-initiation complex and its  transition into DNA replication forks | SpringerLink
Characterization of the dimeric CMG/pre-initiation complex and its transition into DNA replication forks | SpringerLink

CMG helicase structure and translocation mechanism. (a) Low resolution... |  Download Scientific Diagram
CMG helicase structure and translocation mechanism. (a) Low resolution... | Download Scientific Diagram

Structural components of the replisome. The CMG replicative helicase... |  Download Scientific Diagram
Structural components of the replisome. The CMG replicative helicase... | Download Scientific Diagram

Frontiers | The Human Replicative Helicase, the CMG Complex, as a Target  for Anti-cancer Therapy
Frontiers | The Human Replicative Helicase, the CMG Complex, as a Target for Anti-cancer Therapy

Isolation of the Cdc45 Mcm2–7 GINS (CMG) complex, a candidate for the  eukaryotic DNA replication fork helicase
Isolation of the Cdc45 Mcm2–7 GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase

Cryo-EM structures of the eukaryotic replicative helicase bound to a  translocation substrate | Nature Communications
Cryo-EM structures of the eukaryotic replicative helicase bound to a translocation substrate | Nature Communications

The CMG helicase and cancer: a tumor “engine” and weakness with missing  mutations | Oncogene
The CMG helicase and cancer: a tumor “engine” and weakness with missing mutations | Oncogene

CUL2LRR1, TRAIP and p97 control CMG helicase disassembly in the mammalian  cell cycle | EMBO reports
CUL2LRR1, TRAIP and p97 control CMG helicase disassembly in the mammalian cell cycle | EMBO reports

CUL2LRR1, TRAIP and p97 control CMG helicase disassembly in the mammalian  cell cycle | EMBO reports
CUL2LRR1, TRAIP and p97 control CMG helicase disassembly in the mammalian cell cycle | EMBO reports

CMG helicase and DNA polymerase ε form a functional 15-subunit holoenzyme  for eukaryotic leading-strand DNA replication | PNAS
CMG helicase and DNA polymerase ε form a functional 15-subunit holoenzyme for eukaryotic leading-strand DNA replication | PNAS

Unregulated translocation of CMG helicase disrupts the replication... |  Download Scientific Diagram
Unregulated translocation of CMG helicase disrupts the replication... | Download Scientific Diagram